Classical swine fever virus

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swine fever Classical swine fever diagnostic found no national classical swine fever control measures

 

Classical swine fever virus (Hogcholera virus: Swine fever virus) Classical swine fever virus is a ssRNA viruses Flaviviridae pestivirus, its RNA is a single strand. Incubation period of 24-72 hours. Its virus particles were round, the size of 38 ~ 44nm, the nucleocapsid is the three-dimensional icosahedral symmetry, cesium chloride density float 1.15 ~ 1.17g/ml, enveloped. Replicate in the cytoplasm. Not agglutinate red blood cells, and bovine virus diarrhea-associated antigen. The virus is ether sensitive to temperature, ultraviolet light, chemical disinfectants such as strong resistance. Classical swine fever virus in embryos or suckling pig spleen, kidney, bone marrow, lymph nodes, white blood cells, connective tissue or cultured cells of lung tissue, but in these cells do not produce significant lesions. Available NDV enhancement testing (END test) Determination of classical swine fever virus as a method of diagnosis of classical swine fever. Infected with classical swine fever virus vaccine, the immune system may get stronger. At present, the Chinese use Chinese attenuated strains of classical swine fever in rabbits in the world is a better vaccine. Edit this paragraph discovery swine fever Classical swine fever was first discovered in 1833 in the U.S. state of Ohio. In 1885, Salmon and Smith et al for classical swine fever and swine erysipelas and salmonellosis were differential diagnosis. 1903, DeSchweinitz and Dorset two's proven swine fever is a viral pathogen. Hungary Hutyra Koves made of classical swine fever in 1908 hyperimmune serum, indicating that when the European swine fever exists. Japan first discovered in 1909 and began to study classical swine fever (Sasahara, 1970). China when discovered and proved the presence of classical swine fever, there is no clear written records. Approximately in 1925, Southeast University, began developing agricultural serum control of classical swine fever. Edit this paragraph the current swine fever Classical swine fever diagnostic clinical manifestations of subacute, chronic or atypical appearance, sometimes acute emergence can occur throughout the year, but spring and autumn and winter multiple, different ages, gender, breed pigs are likely to occur, only to master the clinical diagnosis and scientific detection methods to correctly diagnose and effectively curb the swine fever epidemic. A clinical diagnosis in large-scale farms, such as pigs successively or simultaneously with several or more pigs fever subside, the spirit of high depression, loss of appetite, general weakness, hindquarters, weakness, constipation, diarrhea late , yellow, green range, sometimes bloody, bleeding spots thin skin, ears purple, the mortality rate is higher, may be initially judged as suspected swine fever. 2, classical swine fever necropsy pathological anatomy changes, you can make the right judgments in the field, such as the lymph nodes showed hemorrhagic see systemic lymphadenitis, marble-like appearance of the cut surface, skin bleeding spots, a bit like bleeding renal anemia, spleen not swollen, bleeding infarction, bladder, throat and gastrointestinal mucosa and serosa epicardial bleeding spots. Chronic swine fever have buckle-shaped swollen colon, and then combined with the analysis of clinical epidemiology, usually make a diagnosis. 3, susceptible pigs vaccinated animal inoculation test is to detect classical swine fever virus, the most sensitive method. Take the incidence of pig's blood or App lymph nodes, spleen, tonsils and other tissues made of emulsions, sterile and inoculated susceptible pigs (10-20Kg), the incidence was observed, and then virus isolation. Usually rabbits cross immunity tests. 4 levels of serum antibodies to classical swine fever immune serum antibodies can provide the basis, in particular ELISA for detection of classical swine fever and mild atypical swine fever has an important role. 5, the detection of CSFV direct immunofluorescence antibody technique is to detect a rapid diagnosis of classical swine fever virus, the method is to take or tonsil pig kidney, and spleen tissues were frozen section or contact piece, fixed with acetone, fluorescent antibody staining was observed under a fluorescence microscope, if these cells were found to have bright green fluorescence, indicating that the memory cells in the classical swine fever virus, can be diagnosed as swine fever. Edit this paragraph without national swine fever Classical swine fever throughout the world, and is highly contagious. As countries in the diagnosis and prevention measures more seriously,Adidas Predator XI, many countries and regions have successively announced the elimination of classical swine fever. According to 1976 data OIE in Paris, has announced that no swine fever following countries: Albania (1973), Bulgaria (1975), Denmark (1933), Finland (1971), the United Kingdom (1971), Hungary (1971), Ireland (1958), Iceland (1953), Luxembourg (1971), Norway (1963), Sweden (1944), Switzerland (1974), Yugoslavia (1973). Japan since 1975 no cases of swine fever, but in 1980 there are many outbreaks. U.S. has also announced that in 1978 no swine fever occurred. Edit this paragraph vaccines and vaccination control measures are an important means of control of classical swine fever,new nike mercurial vapor superfly 2013, including inactivated vaccines and attenuated vaccine. Countries are safe and effective vaccine research efforts. China good selection of immunogenic strain Shimen manufacture of crystal violet? Glycerol vaccines, the former Soviet Union and Eastern European countries has long been respected and used. In addition, China is also the successful cultivation of "54? Ⅲ system" or C series (strain) HCLV vaccine has proved to be a good tool for the eradication of classical swine fever. Kind of drug since 1956, has presented Hungary, the former Soviet Union, Romania and other countries. According to the Hungarian report, proved advantageous than other commercial vaccines for pigs,cr7 cleats 2013, piglets no residual vestiges of power, and have a strong long-lasting immunity. Applications for many years in Europe and other countries, recognized as safe and effective attenuated vaccine strains. [1]